Innovative considerations for efficient multi-(product) use of ProteinA columns
Created by: Jennifer Spiegler, Staff Validation Engineer at Janssen Biologics Leiden, the NetherlandsIn traditional monoclonal antibody (mAb) manufacturing, the first purification process step of crude harvest (obtained from cell culture) is Protein-A Chromatography. This expensive column resin is often under-utilized for clinical or orphandrug products since the chromatography columns are dedicated per product. In this […]
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